Category Archives: The Scripps Research Institute (TSRI)

A new cross-coupling simplifies the synthesis of drug-like molecules

LA JOLLA, CA – March 12, 2018 – Researchers at The Scripps Research Institute (TSRI) have designed a new molecule-building method that uses sulfones as partners for cross-coupling reactions, or the joining of two distinct chemical entities in a programmed fashion aided by a catalyst. The technique, described recently in the journal Science, paves the way toward other new… Read More »

Cells stressed out? Make mitochondria longer

LA JOLLA, CA – March 14, 2018 – Scientists at The Scripps Research Institute (TSRI) have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age. In response to stress, rather than churn out misshapen proteins, our cells activate protective pathways that take an… Read More »

Calibr’s repurposed drug to treat non-viral diarrhea enters into a clinical trial

Cryptosporidiosis is one of the  leading causes of diarrhea in children under the age of 2 in developing countries, and there is no available treatment approved for use in the pediatric population.1 Childhood diarrheal diseases are not only the second leading cause of death in children under 5, causing 525,000 deaths annually, they are  also a leading cause of… Read More »

Graduate program at The Scripps Research Institute earns another top ten ranking

LA JOLLA, CA and JUPITER, FL – Mar. 21, 2018 – The Skaggs Graduate School of Chemical and Biological Sciences at The Scripps Research Institute is ranked among the top ten in the nation according to a recent survey by U.S. News & World Report. This is the 19th year in a row that the program has earned top ten honors.… Read More »

Long thought to only cause a rare disease, this mutation may ward off malaria

The study was led by Shang Ma (left), PhD, and Ardem Patapoutian, PhD, at The Scripps Research Institute. (Photo by Kara Marshall) LA JOLLA, CA – March 22, 2018 – A genetic mutation that may protect people from malaria, but was thought to be rare, is surprisingly common, suggest the findings of a new study led by scientists at… Read More »

Scripps Research discovery paves way for better flu prevention, treatment

LA JOLLA, CA – April 3, 2018 – This year’s flu vaccine has been less effective in protecting people from the most common strain of the virus, compared with recent years. And once people become infected with the flu, there are few good ways to treat it. Now scientists at The Scripps Research Institute have discovered a new… Read More »

Healthy red blood cells owe their shape to muscle-like structures

Discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia LA JOLLA, CA – April 4, 2018 – Red blood cells are on a wild ride. As they race through the body to deliver oxygen, they must maintain a distinct dimpled shape—and bounce back into form even after squishing through narrow… Read More »